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M. C. Ramello

1 paper indexed here

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Open access Aug 2026

C-terminus CD28 phosphorylation, Y218, modulates IL-2 secretion and therapeutic effect of CAR-T cells.

CD28 is a co-stimulatory component of several second-generation chimeric antigen receptor (CAR)-T cells, providing signals essential for T cell proliferation, survival, and cytokine secretion. However, the specific contribution of individual CD28 intracellular motifs to CAR-T cell function remains incompletely understo...

Elena Martinez-Planes, M. C. Ramello, Miguel G. Fontela et al. · 0 citations

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