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Oct 2026

Blood proteome-wide Mendelian randomization reveals molecular pleiotropy in coronary artery disease.

BACKGROUND AND AIMS Coronary artery disease (CAD) is a common cardiovascular disease characterized by the development of atheromatous plaques. Recent large-scale association study (GWAS) offers an opportunity to better understand the underpinnings of this pathology. METHODS To investigate the underlying molecular mec...

Louis-Hippolyte Minvielle Moncla, S. Mathieu, M. Briend et al. · 0 citations
Sep 2026

Synonymous codon usage shapes ERα function through specialized translational programs during breast cancer progression.

It is shown that the transition of breast cancer cells from quiescent, differentiated states towards proliferative, less differentiated phenotypes, is accompanied by a systematic shift from G/C3- to A/U3-biased codon usage, identifying synonymous codon usage as a previously unrecognized mechanism linking translational...

Tamara Fernández-Calero, Raphaël Métivier, F. Percevault et al. · 0 citations

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