Author

M. Breunig

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Open access Aug 2026

Hydrogel crosslinking mechanisms influence the release and functional delivery of lipid nanoparticles

Investigating the release, stability, cellular uptake, and transfection capability of LNPs released from four hydrogel systems representing distinct crosslinking mechanisms shows that hydrogel composition is a critical determinant of mRNA-LNP release, stability, and functional delivery.

Andreas G. Schreiber, Felix Hauswirth, Leon Reger et al. · bioRxiv · 0 citations

Open access Jul 2026

Localized delivery of coding nucleic acids into adherent cells by in situ electroporation: integrated impedance-based monitoring allows for loss-of-function or gain-of-function screening

The combination of ISE, specific NAs and impedance-based cell monitoring paves the way for a new class of gain-of-function or loss-of-function experiments.

Anne-Kathrin Grimm, Sonja Balk, A. Göpferich et al. · Scientific Reports · 0 citations