Author

M. Bonfanti

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Open access Oct 2026

Single-cell profiling of dysfunctional NK cells in COVID-19: from immunization to acute infection and beyond

Vaccination and natural infection with Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) confer immune protection through distinct mechanisms, however, their effects on Natural Killer (NK) cell responses remain poorly understood, particularly in relation to COVID-19 disease severity. NK cells, key mediat...

Alessandro Frigo, S. Terzoli, Paolo Marzano et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

Stem cell morphology defines functional heterogeneity and therapeutic vulnerabilities in glioblastoma.

BACKGROUND Glioblastoma (GBM) is an aggressive brain tumor and an unmet clinical need due to its invasiveness and therapy resistance. These features are driven by glioblastoma stem-like cells (GSLCs), which exhibit remarkable functional heterogeneity. While transcriptional profiling has helped define this heterogeneity...

C. Barelli, M. Bonfanti, F. Mirabella et al. · Neuro-Oncology · 0 citations

Open access Aug 2026

The human RNA-DNA interactome is cell type-specific and dynamic

The RNA-DNA interactome is established as a new genome regulatory layer that defines and maintains cellular identity and behavior and is shown to be highly dynamic yet reproducibly organized in cell-type specific networks.

A. Lambolez, P. Sahlén, Wenjing Kang et al. · bioRxiv · 1 citation