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Author

M. Al Eissa

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4 papers indexed here

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Open access Sep 2026

HLA allelic variation and COVID-19 severity in a Kuwait-based population: a high-resolution immunogenetic study

Background Human leukocyte antigen (HLA) polymorphisms play a vital role in antiviral immunity, but their influence on COVID-19 severity differs significantly among ethnic groups. T-cell responses are essential for clearing SARS-CoV-2, yet the immunogenetic factors underlying the diverse clinical outcomes in COVID-19,...

Monera Alrukhayes, Nada Al-Shatti, Almunther Alhasawi et al. · 0 citations
Review Open access Sep 2026

A framework for population health observatory from a global perspective: proposed preliminary maturity model and key performance indicators

Background Population health observatories (PHOs) have emerged as fundamental pillars of modern public health governance, enabling the transformation of fragmented, multidimensional health data from multiple centres into evidence-informed policymaking and development, strategic planning and actionable intelligence for...

M. Al Eissa, Shaker A. Alomary, A. Assiri · 0 citations
Open access Sep 2026

Metabolic Signatures Associated with COVID-19 Vaccination in Serum from Healthy Individuals

Background: COVID-19 vaccines have proven effective in reducing severe disease and mortality from SARS CoV-2 infection. The underlying molecular mechanisms and alterations in the human serum metabolome influencing the effectiveness and development of immunity remain unclear. Methods: Serum samples were collected from 2...

M. Al Eissa, Refat M. Nimer, Reem H. Almalki et al. · 0 citations
Review Open access Jul 2026

Durability of COVID-19 vaccine-induced immunity in Saudi Arabia: evidence, gaps, and implications for Hajj and mass-gathering preparedness

The review highlights those circulating antibodies and neutralizing activity decline after vaccination, particularly against antigenically divergent variants, whereas memory B-cell responses and CD4+ and CD8+ T-cell immunity generally provide more durable protection against severe disease.

Leena E. Azhar, Ahdab A. Alsaieedi, M. Al Eissa et al. · 0 citations

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