Author

M. Afshani

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

CFTR correctors suppress Ca²⁺-cAMP signaling and cyst growth in primary cultures of ARPKD cholangiocytes.

Autosomal recessive polycystic kidney disease (ARPKD) is a severe ciliopathy caused by mutations in Polycystic kidney and hepatic disease 1 gene (PKHD1), resulting in progressive renal and hepatobiliary disease for which effective targeted therapies are lacking. Although reduced cystic fibrosis transmembrane conductanc...

Abhishek Sharma, M. Afshani, Tanvi Sharma et al. · Cell Calcium · 0 citations

Aug 2026

Durational Study of Persistent Transduction of Rhesus Macaque Lung and Other Organs Following Single Dosing with AAV1-CFTR

The findings indicate sustained gene transfer and transduction for at least 180 days following a single AAV1 administration to the primate lung, with minimal immunopathology, which supports the potential feasibility of extended dosing intervals and informs the development of repeatable AAV-based gene therapies for CF.

Prajita Paul, Tanvi Sharma, M. Afshani et al. · Human Gene Therapy · 0 citations