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Author

M. Adamo

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Oct 2026

Definition and Prognosis of Mitral Regurgitation in Transthyretin Amyloid Cardiomyopathy: A Multicenter International Cohort Study.

BACKGROUND In transthyretin amyloid cardiomyopathy, mitral regurgitation (MR) severity may be underestimated by conventional (semi-)quantitative echocardiographic criteria due to restrictive low-flow hemodynamics. We sought to define and validate disease-specific MR risk thresholds and compare their prognostic performa...

L. Hauptmann, C. Kronberger, S. Schwarting et al. · 0 citations
Case report Open access Sep 2026

Staged Transcatheter Treatment of Combined Aortic and Mitral Regurgitation: A Downstream Approach.

BACKGROUND Concomitant severe aortic (AR) and mitral regurgitation (MR) affects up to 25% of patients with aortic valve disease and portends poor prognosis. Evidence on a sequential downstream approach in native AR is limited. CASE SUMMARY We report 4 patients with high surgical risk (mean age 82 years, Society of Th...

M. Massussi, Mariafrancesca Forquet, Paolo Scurti et al. · 0 citations
Aug 2026

Conduction Disturbances and Permanent Pacemaker Implantation After TAVR With Self-Expanding Devices: The CONNAVIPRO Study.

BACKGROUND The Evolut and the Navitor transcatheter heart valves (THVs) represent the most widely used self-expanding implanted valves. Despite a similar implant concept, they markedly differ in design and hemodynamic performance. In both THVs, conduction disturbances following transcatheter aortic valve replacement (T...

Enrico Poletti, O. Oliva, Ahmad Hassan et al. · 0 citations
Open access Aug 2026

Prognostic Value of NYHA Functional Class in Tricuspid Valve Transcatheter Edge-to-Edge Repair: Insights From EuroTR.

BACKGROUND In patients undergoing tricuspid valve transcatheter edge-to-edge repair (T-TEER) for tricuspid regurgitation (TR), NYHA functional class guides assessment, but real-world data on its prognostic value and determinants of symptomatic response remain limited. OBJECTIVES The objective of the study was to asse...

Charlotte Wolff, P. Sagmeister, K. Fengler et al. · 0 citations
Open access Sep 2026

New Evidence in Heart Failure: 2026 Update.

Therapeutic developments continue to reshape HF management across the spectrum of left ventricular ejection fraction, and support the transition from a predominantly phenotype-based approach towards a more personalized and biologically informed model of HF care.

Valentino Liguori, Angelica Rizzello, M. Adamo et al. · 0 citations
Review Open access Aug 2026

Mitral Regurgitation in Contemporary Practice: From Diagnosis to Management

An integrated, stepwise management algorithm is proposed that incorporates early risk markers, including natriuretic peptides, to guide the timing of intervention before irreversible myocardial damage occurs and enables more precise patient phenotyping and treatment tailoring.

C. Gaspardone, Paolo Costa, G. Barone et al. · 0 citations

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