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Deep brain stimulation (DBS) is one of the most effective surgical interventions for neurodegenerative diseases (NDDs), particularly Parkinson's disease (PD). Although the technique originated in the 1950s and 1960s to treat chronic pain and psychiatric disorders, modern advancements targeting the subthalamic nucleus (...
The findings indicate that conventional sequencing techniques are inadequate for detecting cell-specific dysfunctions, particularly within rare cell populations, and paves the way for the identification of new therapeutic targets to correct the dysfunction of specific cell populations.
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