Review
Open access
Jul 2026
The cGAS–STING pathway in tumor immunity: dual roles, regulatory mechanisms, and precision therapeutic strategies
This review systematically elucidates the molecular activation mechanisms of the cGAS–STING pathway and its complex regulatory networks within tumors, with a particular focus on analyzing its dual functions—tumor immune surveillance versus tumor promotion—and the determining factors involved.
Haiyan Jiang, Zhanzhan Li, Xia Li et al.
· Frontiers in Pharmacology · 2 citations