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Luis E. Rosas-Vidal

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Open access Oct 2026

Good vibes keep worries at bay: a prefrontal-hypothalamic pathway engages positive affect to mitigate fear

This study shows that key cortico-hypothalamic projections manage extinction retrieval and positive affect to promote fear extinction, and discovered that SIRT1-expressing mPFC-SuM extinction-recruited projections control extinction relapse vulnerability.

Quan-Son Eric Le, Luis E. Rosas-Vidal · 0 citations

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