Open access
Sep 2026
Emerging Roles of TMEM97/Sigma-2 Receptor in Breast Cancer Endocrine Resistance: Links to mTOR Signaling and Cholesterol Metabolism
Work surrounding the sigma-2 receptor (σ2R) and its potential role in endocrine therapy resistance pathways, including PI3K-mTOR signaling and cholesterol metabolism is summarized.
Lucy M. Fitzgibbons, Yuan-Qin Zhang, Xiang-Wei Fang et al.
· Kinases and Phosphatases · 0 citations