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Author

Luciana Mezzano

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Open access Oct 2026

NAD⁺ modulation by nicotinamide riboside enhances CD8⁺ T-cell metabolic fitness and effector function during Trypanosoma cruzi infection and improves parasite control

Chagas disease, caused by the parasite Trypanosoma cruzi, remains a major health concern, with effective immune control relying heavily on CD8⁺ T cells. However, the metabolic factors that regulate CD8⁺ T cell function during infection are not well understood. Acute T. cruzi infection induced metabolic remodeling in pa...

Florencia Hellriegel, Camila Fontanari, R. E. Baigorrí et al. · 0 citations

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