Innate immune transcriptomic remodeling across clinical stages of bovine leukemia virus infection.
Bovine leukemia virus (BLV) is an oncogenic deltaretrovirus that establishes lifelong infection in cattle and may progress from asymptomatic carriage to persistent lymphocytosis (PL) and lymphoma. Although adaptive immune alterations have been widely studied, the stage-specific transcriptional landscape of innate immun...