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Luca Pellegrini

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Sep 2026

How to grow a filament: Lessons from the RAD51 paralogs toolbox.

In this issue of Molecular Cell, Koo et al.1 describe how the yeast Rad55-Rad57-SHU complex dynamically nucleates Rad51 filaments on DNA. Functional coupling between Rad55-Rad57 and Rad51 on ssDNA seeds filament growth, whilst ATP hydrolysis promotes complex turnover.

Luca Pellegrini · 0 citations

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