Review
Oct 2026
Engineering microbial platforms for diversified biosynthesis of antidepressant tryptophan-derived neuroactive compounds.
Tryptophan-drived neuroactive compounds, including serotonin, melatonin, 5-hydroxytryptophan (5-HTP), psilocybin, and related indole derivatives, represent an important class of therapeutics for depression and other neuropsychiatric disorders. However, conventional production through chemical synthesis or natural extra...
Rui-Rui Xu, Feng-Ling Yang, Lu-Yao Zhang et al.
· Biotechnology Advances · 0 citations