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Author

Lu Liu

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Open access Sep 2026

Elevated plasma eosinophil-derived neurotoxin is associated with echocardiographic pulmonary vascular involvement in stable COPD

Background Pulmonary vascular involvement is an important dimension of chronic obstructive pulmonary disease (COPD) heterogeneity, but its biological features may not be fully represented by airflow limitation, gas-transfer impairment, or resting hypoxemia. eosinophil-derived neurotoxin (EDN) is a circulating eosinophi...

Xiao-Chen Hu, Fu-Shi Dong, Q. Song et al. · 0 citations
Open access Aug 2026

Normoalbuminuric and albuminuric diabetic kidney disease exhibit divergent renal proteomic characteristics: implications for management.

BACKGROUND The pathogenesis of diabetic kidney disease (DKD) is complex. Normoalbuminuric diabetic kidney disease (NADKD) is a special subtype of DKD that often progresses insidiously without detectable albuminuria, posing diagnostic and therapeutic challenges. Its pathogenesis remains unclear. Proteomic analysis of re...

Lu Liu, Yan Zhao, Yuan Li et al. · 0 citations
Open access Aug 2026

Serum metabolic characteristics of interstitial lung disease: a potential link between endocrine aging and gut-derived metabolites

Untargeted metabolomics has revealed significant systemic metabolic dysregulation in ILD and the biomarkers and “metabolic-immune-endocrine” interaction patterns identified offer potential leads for early diagnosis and targeted treatment, which require validation in larger cohorts.

Lu Liu, Xin-Yi Wang, Jinling Xiao et al. · 0 citations

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