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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Lu Han

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2 papers indexed here

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Aug 2026

Targeting viral Fe-S clusters with TEMPOL confers broad-spectrum anti-coronavirus activity.

Coronaviruses (CoVs) can cause severe respiratory and enteric diseases, posing major threats to human health and the livestock industry. However, the host metabolic mechanisms underlying viral replication remain unclear. Using porcine epidemic diarrhea virus (PEDV) as the primary model, this study investigated the role...

Le-Yu Hu, Letao Gao, Xing-Wei Fu et al. · 0 citations
Open access Sep 2026

PEDV envelope protein promotes viral replication by remodeling host iron homeostasis via the TRIM28-KLF15-FPN axis

ABSTRACT Porcine epidemic diarrhea virus (PEDV), a member of the Alphacoronavirus genus, causes severe enteric disease with up to 100% mortality in suckling piglets. Iron is an essential micronutrient for the replication of various pathogens, including viruses, which hijack host iron resources to support their prolifer...

Le-Yu Hu, Ru Tian, Letao Gao et al. · 0 citations

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