Ginsenoside Rb1 regulates macrophage-spermatocyte crosstalk by targeting the TNF-α/NF-κB/IL-6 axis to alleviate sepsis-induced testicular injury.
Sepsis is a multiple organ dysfunction syndrome caused by the dysregulated host response to infection, and this condition could lead to testicular injury and cause male infertility. Testicular macrophages play a key role in testicular injury caused by sepsis. This study focused on the communication mechanism between ma...