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Author

Lorenza Esposito

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Open access Aug 2026

Comprehensive transcriptomic profiling reveals impaired polyamine metabolism as a contributor to age-related muscle decline

A spatial transcriptomic atlas of skeletal muscle from young and aged mice is presented, resolving transcriptional reprogramming across fiber types and tissue compartments and revealing alterations in sarcomeric organization, excitation-contraction coupling, oxidative stress responses, and fiber type-specific metabolic...

Veronica Ruggieri, Andrea Bracaglia, Lorenza Esposito et al. · 0 citations

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