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Author

Long-Ze Sha

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Open access Sep 2026

Acute sepsis seeds long-lived brain-resident macrophages that drive microglia-dependent chronic neuroinflammation through PTN signaling

Early-life severe infection is increasingly recognized as a cause of persistent cognitive impairment; however, the mechanisms by which peripheral immune cells drive and sustain chronic neuroinflammation remain poorly understood. Although infiltrating peripheral myeloid cells are generally considered transient populatio...

Er-Ning Zhang, Long-Ze Sha, Cai-Yun Zhu et al. · 0 citations
Open access Sep 2026

Spatiotemporal Atrophy Subtypes in Alzheimer's Disease: Neurodegenerative-Vascular Associations and Potential Prognostic Value.

Bomarker-confirmed AD comprised internally reproducible atrophy trajectories with distinct cognitive, vascular, and molecular profiles and may complement fluid biomarkers and conventional volumetry for patient stratification and prognosis.

Chen-Hui Mao, Yu-Yue Qiu, Bo Li et al. · 0 citations

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