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Long-Yan Yang

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Review Open access Oct 2026

Mechanistic insights into lactate-driven pathogenesis in diabetic kidney disease

Diabetic kidney disease (DKD) remains the leading cause of end-stage renal disease worldwide, yet current therapeutic approaches fail to fully halt its progression. Emerging evidence identifies lactate not merely as a glycolytic byproduct, but as a critical signaling molecule that drives DKD pathogenesis via lysine lac...

Shi-Hao He, Long-Yan Yang, Rui-Li Yin · 0 citations

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