Characterization of a neral reductase from Serratia marcescens: Structure-guided engineering and construction of an efficient whole-cell cascade for (S)-citronellol synthesis.
In this study, a previously uncharacterized neral reductase (an ene-reductase), SmNR (Serratia marcescens Neral Reductase), belonging to the Old Yellow Enzyme family, was identified and functionally characterized from Serratia marcescens HBQA7. SmNR efficiently catalyzes the asymmetric reduction of neral to produce (S)...