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Sep 2026

Targeting Tumor–CAFs Crosstalk to Reverse Drug Resistance and Immunosuppression Through Cuproptosis

Chemotherapy resistance and immunosuppression are the current key bottlenecks in tumor treatment. In the tumor microenvironment (TME), cancer‐associated fibroblasts (CAFs) secrete dense extracellular matrix and various immunosuppressive factors, forming a dynamic “tumor–CAFs crosstalk”, which drives the progression o...

Qing-Qing Xu, Shuai-Peng Feng, Dong-Lin Bian et al. · 0 citations
Aug 2026

Copper/tetrasulfide co-doped mesoporous organosilica for multimodal imaging-guided photothermal tumor stiffness modulation and synergistic chemo-chemodynamic therapy of triple-negative breast cancer.

Overall, DCMP provides a multimodal imaging-guided nanotherapeutic strategy that combines chemical tumor killing with physical tumor matrix modulation to enhance chemo-chemodynamic-photothermal antitumor therapy.

Long Wan, Lu Zou, Dong-Lin Bian et al. · 0 citations

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