Long-Mei Yu

Dysregulated IL-2 signaling and T-cell subset shifts are associated with eosinophilic esophagitis activity

Eosinophilic esophagitis (EoE) is a chronic immune-mediated disorder of the esophagus. However, the T-cell transcriptional programs distinguishing active disease from remission remain incompletely understood. In this study, we applied single-cell RNA sequencing to esophageal biopsies obtained from normal subjects and p...