Author

Long-Hao Zhang

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Case report Open access Oct 2026

Intrahepatic intraductal papillary neoplasm of the bile duct with low-grade dysplasia presenting as high biliary obstruction and hepatolithiasis: a case report

Background Intraductal papillary neoplasm of the bile duct (IPNB) is an uncommon biliary epithelial neoplasm and an important precursor lesion of cholangiocarcinoma. The educational value of this case lies in demonstrating that IPNB may be clinically masked by hepatolithiasis and biliary obstruction, creating a signifi...

Jian-Kai Long, Jing-Nan Xue, Nan-Zi Xie et al. · Frontiers in Medicine · 0 citations

Review Open access Sep 2026

Comparative prognostic performance of triglyceride-glucose-adiposity indices for mortality in adults with metabolic dysfunction-associated steatotic liver disease

Composite indices integrating insulin resistance and adiposity may improve mortality risk stratification in metabolic dysfunction-associated steatotic liver disease (MASLD). We evaluated eight triglyceride-glucose (TyG)-related indices in 6,159 U.S. adults with MASLD from the 1999–2018 National Health and Nutrition E...

Kai Zhang, Na-Ni Long, Long-Hao Zhang et al. · Scientific Reports · 0 citations

Review Open access Aug 2026

From the invasive front to organotropic pre-metastatic niches: spatial immune regulatory networks governing cholangiocarcinoma dissemination and metastasis-intercepting immunotherapy

“metastasis-intercepting immunotherapy” is used as an author-defined conceptual framework for strategies intended to prevent or disrupt the immune–stromal conditions that enable dissemination and colonization, rather than merely shrink established metastatic lesions.

Longhao Zhang, Kai Zhang, Zhi-Hong Chen et al. · Frontiers in Immunology · 0 citations