Review
Open access
Jul 2026
Strategies and mechanisms of precision genome engineering: From gene editing to genome writing
Genomic manipulation has advanced from stochastic nuclease‐mediated disruption toward programmable, deterministic precision. Early clustered regularly interspaced short palindromic repeats (CRISPR) strategies enabled targeted mutagenesis through double‐strand breaks; however, their therapeutic application is limited by...
Ke-Rui Huang, Jianhong Tian, Wen-Yan Zhao et al.
· iMetaOmics · 3 citations