Lixiang Fu

Novel Curcumin Derivatives as Potent FtsZ-Targeting Bactericides against Rice Bacterial Leaf Blight.

Rice bacterial leaf blight (BLB), caused by Xanthomonas oryzae pv. oryzae (Xoo), poses a serious threat to global rice production. Given the critical role of filamentous temperature-sensitive protein Z (FtsZ) in bacterial cell division, thirty-five curcumin derivatives were designed targeting XooFtsZ for combating BLB....