A Seven Amino Acid Long Region in the Cardiac Cav1.2, Encompassing Ser1487, Is Essential for Mice Embryonic Development and “Fight or Flight” Responses
The cardiac calcium channel Cav1.2 is essential for embryonic development, cardiac excitation–contraction coupling, and the “Fight or Flight” response. Regulation of Cav1.2 by protein kinase A (PKA) phosphorylation is critical to this process, though the underlying mechanism remains contentious. We previously identifie...