Author

Liurong Fang

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Open access Sep 2026

Interaction between DEAD-box RNA helicase 10 and influenza PB1 polymerase selectively regulates influenza A virus replication

This work defines DDX10 as a potential host factor that differentially supports influenza polymerase activity, revealing a specific molecular interface that contributes to the replication efficiency of distinct viral subtypes in human cells and providing insight into host-adaptive mechanisms.

R. Ullah, Wei Chen, Ling-Kai Zhang et al. · Journal of Virology · 0 citations

Open access Sep 2026

Coronavirus Nsp5‑mediated dual‑site cleavage of GSDMA modifies its antiviral and proinflammatory functions

It is shown that GSDMA deficiency increases viral loads but reduces inflammation, tissue damage, and mortality upon infection, suggesting that disease severity is driven more by inflammation than by viral load.

Chen-Yu Li, Yu-Xi Zhao, Yu-Chen Zhang et al. · PLoS Pathogens · 0 citations

Aug 2026

Porcine Serum Amyloid A2 Blocks PRRSV by Directly Targeting Virion-Associated PIP2 and GP5.

Porcine reproductive and respiratory syndrome virus (PRRSV) is a significant pathogen in swine, causing substantial economic losses globally. The host acute-phase response to PRRSV infection and its role in antiviral defense remain poorly understood. In this study, we identify serum amyloid A2 (SAA2) as a key acute-pha...

Shuai Li, Yuanxiang Xiong, Liurong Fang et al. · Antiviral Research · 0 citations