Systemic regulation of rheumatoid arthritis by mesenchymal stem cells: from immune homeostasis to microbiota modulation
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis and progressive joint destruction. Although conventional therapies effectively alleviate clinical symptoms, they are largely incapable of reversing irreversible joint damage and the underlying immune dysregulation. Mesenchymal stem ce...