Liting Lyu

Multi-omics analysis revealed oil accumulation and compositional remodeling in Rhodosporidium toruloides under nitrogen limitation.

Microbial lipids from oleaginous yeasts are promising sustainable alternatives for biofuel and food applications. However, rational engineering requires a comprehensive understanding of both lipid yield and molecular composition, together with their regulatory basis. In this study, high-coverage lipidomics integrated w...

Acyl-Carrier-Protein-Engineering Rewires the Fatty Acid Profile in the Oleaginous Yeast Rhodotorula toruloides

The oleaginous yeast Rhodotorula toruloides has emerged as a host for the production of lipids mainly consisting of long-chain fatty acid triacylglycerides as alternative feedstock for oleochemicals and biofuels. The R. toruloides fatty acid synthase (RtFAS) complex contains two acyl carrier protein (ACP) domains withi...

Metabolic unlocking of lycopene accumulation in the oleaginous yeast Rhodotorula toruloides