Review
Open access
Sep 2026
Chemical and Biological Determinants of PEG-Lipid Shedding From Therapeutic Nanoparticles.
Key factors that link PEG-lipid composition and nanoparticle architecture to desorption kinetics and biological outcomes are identified and provide guidance for the design of PEGylated nanomaterials with improved control over interfacial stability, immune recognition, and functional performance.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti
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