Lining Lu

The pair of fatty acid degradation regulator (FadR)-characterized pseudo-palindromic motifs spacing with 11 bp contribute unequally to the DNA binding ability of the HTH-type transcriptional regulator Rv0494 from Mycobacterium tuberculosis H37Rv.

Transcriptional regulation is an effective way for bacteria to respond to various environmental challenges, such as carbon source scarcity. Acting as a transcription factor belonging to the fatty acid degradation regulator (FadR) subfamily, the HTH-type transcriptional regulator Rv0494 is reported to function in persis...