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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Lingyun Long

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Sep 2026

Abstract IA05: Biology and therapeutic targeting of NUP98 fusion oncoprotein condensates

NUP98 fusion oncoproteins (FOs) define a high-risk subset of pediatric acute myeloid leukemia, for which more effective therapies are urgently needed. NUP98 FOs involve the intrinsically disordered, N-terminal region of NUP98 and the C-terminal region of one of over 30 identified partner genes. These partner genes co...

N. Michmerhuizen, Ella Monfort, Z. G. Soares et al. · 0 citations
Jul 2026

ARID1A Stimulates Notch-TLL1 Signaling to Induce Cancer-Associated Fibroblast Activation and Intrahepatic Cholangiocarcinoma Development.

Intrahepatic cholangiocarcinoma (ICC) is a lethal hepatic malignancy characterized by a prominent desmoplastic stroma. Here, we demonstrated that ARID1A, a core component of the SWI/SNF protein complex, is upregulated in ICC and plays an oncogenic role. Mechanistically, ARID1A stabilized NICD1 protein by inhibiting AMP...

Sheng Xu, Jing-Yi Huang, Kang Wang et al. · 0 citations

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