Oct 2026
BTRC aggravates FFA-induced lipid accumulation in MASLD via G3BP1 degradation and subsequent SIRT6 mRNA destabilization.
BACKGROUND Metabolic dysfunction associated steatotic liver disease (MASLD) features hepatic steatosis and lipotoxicity, yet its molecular mechanisms remain incompletely understood. How post-transcriptional regulation and protein turnover shape hepatocyte lipid homeostasis in MASLD requires further elucidation. METHO...
Dong-Mei Zou, Liang Liu, Cheng-Yang Yang et al.
· Biochimica et Biophysica Act... · 0 citations