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Ling-Xi Ye

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Aug 2026

UNCX/SIN3A-Mediated H4K8 decrotonylation suppresses FOXO3 to drive TNBC progression and docetaxel resistance.

Uncoordinated homeobox (UNCX) is upregulated in docetaxel-resistant breast cancer cells, genomically amplified in breast cancer, and associated with poor survival in breast carcinoma patients, and established as a pivotal epigenetic regulator of TNBC progression and chemoresistance.

Song-Fu Shi, Dong Yan, Lixin Zhao et al. · 0 citations

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