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Review Open access Sep 2026

Emerging Roles of tRNA Modifications in Translational Adaptation of Human Fungal Pathogens

This Review examines how studies connect modification chemistry and substrate tRNAs with translation, protein output and infection phenotypes in Aspergillus fumigatus, Candida albicans and Cryptococcus neoformans and draws on mechanistic studies from model organisms and plant-pathogenic fungi to clarify translational l...

Yu-Qi Zhu, Jia-Qi Chen, Xin-Ran Li et al. · 0 citations
Open access Oct 2026

Large-scale genome re-annotation uncovers pathogen-specific lncRNA regulators of fungal growth and virulence

Invasive fungal infections pose a serious global health threat. Although core cellular processes are broadly conserved across fungi, only a small fraction of known species cause severe human disease, suggesting that pathogenicity may depend in part on pathogen-specific regulators. However, such elements remain poorly u...

R. Gao, Zhen-Xiu Liu, Han Tang et al. · 0 citations

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