Ling Kong

Apigenin promotes neuronal norepinephrine release via GPR30/PLCβ1-Ca2+-Syt1 signaling to enhance astrocytic lactate and exert neuroprotection in D-galactose-induced cognitive impairment

AD, a prevalent neurodegenerative disorder clinically defined by progressive cognitive impairment, is pathologically featured by early dysfunction of the locus coeruleus, depletion of noradrenergic (NE) neurons, and dysregulated astrocytic glycogen metabolism, which collectively compromise patients’ daily functioni...

Influenza virus research in an era of emerging respiratory threats: host–virus interactions, surveillance technologies, antiviral management and resistance, and vaccine preparedness

Seasonal epidemics, zoonotic spillover, antiviral resistance, and pandemic risk continue to make influenza a major challenge for respiratory preparedness. The recent spread of highly pathogenic avian influenza A(H5N1) in mammalian hosts has made it increasingly important to consider molecular adaptation, surveillance,...

Imbalance of the Regulated Cell Death and Autophagic Network: A Core Mechanism Driving Toxicological and Ischemic Myocardial Injury and a Target for Intervention with Traditional Chinese Medicine

Integrative multi-omics analysis unravels the metabolic landscape and reveals serum biomarkers for early diagnosis of hyperuricemia

The core metabolic and protein regulatory networks of HUA are revealed, and a novel serum metabolite panel for the diagnosis of HUA is identified, providing new insights for improved clinical diagnosis and management.