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Ling-Fei Hu

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Open access Sep 2026

Dynamic orchestration of structural and immune cells in acute Pseudomonas aeruginosa pneumonia revealed by time-resolved single-cell and spatial transcriptomics

Background Pseudomonas aeruginosa pneumonia triggers a complex, dynamic host response, yet the cellular coordination of inflammation and repair remains poorly defined. Methods We performed time-resolved single-cell RNA sequencing (scRNA-seq) on murine lungs across five timepoints (0–96 h post-infection) and integrated...

Fu-Liang Zong, Yan Wang, Ling-Fei Hu et al. · 0 citations

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