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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Linzhang Huang

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3 papers indexed here

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Open access Sep 2026

Chinese metabolism research 2020 − 2025: from mechanistic discovery to causal, translational systems biology

Metabolic dysregulation is a central pathophysiological link to diverse diseases, posing growing challenges to global health. Confronted with the rising burden of obesity, diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD), and other metabolic disorders amidst rapid socioeconomic transformatio...

Tong-Jin Zhao, Hao-Bin Ye, Jun-Feng Bi et al. · 0 citations
Open access Sep 2026

Lactate Receptor Activation Alleviates Senescence and Preserves Homeostasis of Aged Arteries

These findings identify age-associated loss of GPR81 as a driver of vascular metabolic dysfunction and cellular senescence and establish pharmacological GPR81 activation as a promising therapeutic strategy for preserving vascular homeostasis and mitigating age-associated cardiovascular disease.

Yu-Lun Wu, Hamsa Vardini Senthil Kumar, Sai Harsha Bhamidipati et al. · 0 citations
Jul 2026

Chem-Stamp Empowered Discovery of a Novel ATRA-Based LDLR Up-Regulator for the Treatment of Atherosclerosis.

Natural products and their derivatives have long served as a prolific reservoir for drug discovery. All-trans retinoic acid (ATRA) regulates lipid metabolism and shows anti-atherosclerotic potential, but its application is limited by poor drug-like properties and retinoid-related toxicity. Here, an allene-based Chem-St...

Shanshan Wang, Jia-Rui Zhang, Weiyi Wang et al. · 0 citations

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