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Lin-Yu Li

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Sep 2026

A Non-Metallic DNA Intercalator from Pyronine-Aloperine Conjugation Reverses Cisplatin Resistance in Ovarian Cancer

Cisplatin (DDP) resistance remains a key factor contributing to the high mortality rate among ovarian cancer patients. The Pt(II)−DNA covalent adduct is prone to removal through changes in gene expression in tumor cells, resulting in DDP resistance. To address this challenge, developing a non-metallic DNA intercalato...

Ling-Li Wang, Xin-Tong Zhu, Lin-Yu Li et al. · 0 citations

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