Open access
Oct 2026
Sub-consensus haploid variant calling in long-read sequencing technology
Background Next-generation sequencing (NGS) is vital for tracking viral evolution during outbreaks. Oxford Nanopore Technologies (ONT) offers long-read, cost-effective sequencing, but accurate sub-consensus variant detection remains challenging. LoFreq, a widely used caller for sub-consensus variant calling in haploid...
Xavier Zair, Andreas Wilm, Miles C. Benton et al.
· PLoS ONE · 0 citations