Jul 2026
Abstract B042: A differentiation-driven migration program in rhabdomyosarcoma (RMS) is governed by a BRD1-MYOG transcriptional axis
This work identified BRD1, a bromodomain-containing transcriptional regulator, as a previously unrecognized driver of RMS cell migration and defined a previously unrecognized regulatory circuit in which BRD1 promotes a MYOG-driven, differentiation-associated migratory state.
Andrea D. Largent, Yadong Wang, Abraham Hengyucius et al.
· Cancer Research · 0 citations