Review
Open access
Aug 2026
The Role and Mechanistic Effects of Gut Microbiota Metabolites in Immunotherapy for Hepatocellular Carcinoma
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced hepatocellular carcinoma (HCC), but low response rates and drug resistance remain major clinical challenges. Recent data underscore the gut-liver axis as a major determinant of therapeutic outcomes, particularly amid an epidemiological tr...
Y. Chan, Pengde Lu, Jiaqi Zou et al.
· Cancer Biome and Targeted Th... · 0 citations