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Lin Xiao

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Open access Oct 2026

Performance Characteristics for Flow Cytometric Enumeration of Peripheral Blood Lymphocyte Subsets under Harmonized Laboratory Conditions: A Multicenter Study.

BACKGROUND Flow cytometric enumeration of peripheral blood lymphocyte subsets (EPBLS) is essential for disease management, yet standardized validation criteria are lacking. We defined key performance characteristics under harmonized conditions to support criteria development. METHODS 205 whole blood samples and 54 qu...

Lin Xiao, Yuan Wang, Yi Li et al. · 0 citations
Open access Aug 2026

Integrative multi-omics analysis reveals LLPS-associated CLEC2D⁺AR⁻ tumor-cell states linked to early adaptive progression toward castration resistance in prostate cancer

Findings provide a conceptual link between LLPS biology, AR-independent tumor-cell plasticity, and microenvironmental remodeling in CRPC, while nominating CLEC2D as a candidate marker and potential therapeutic target requiring further experimental validation.

Ze Cheng, Jinhua Yan, Shunkang Xue et al. · 0 citations

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