Author

Lin-Qiu Han

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Open access Sep 2026

m6A writer METTL14 restricts Mycobacterium tuberculosis infection by promoting TAX1BP1-mediated autophagy in macrophages.

N6-methyladenosine (m6A) modification plays a crucial role in regulating immune responses against Mycobacterium tuberculosis (Mtb) infection, but the underlying mechanisms remain unclear. Here, we analyzed m6A regulatory gene expression in GEO dataset GSE139825 and validated the finding in THP-1-derived macrophages. Bi...

Nueramina Tieliwaerdi, Zhen-Zhen Pan, Nigela Elihamu et al. · Immunobiology · 0 citations

Review Open access Sep 2026

The ageing microenvironment in sarcopenia: early alterations and targeted therapeutic strategies

Key early alterations in sarcopenia are summarized, including dysregulated immune homeostasis, cellular senescence and the senescence-associated secretory phenotype, depletion and dysfunction of muscle satellite cells, disruption of the regenerative niche, mitochondrial dysfunction, impaired proteostasis and neuromuscu...

Liang-Ping Zhang, Guang-Yang Li, Long Long et al. · Frontiers in Immunology · 0 citations