Open access
Oct 2026
Inclisiran ameliorates diabetes-associated skeletal muscle remodeling through modulation of FOXO1/PDK4 and ER stress-UPR signaling
Preliminary molecular and histological evidence is provided supporting a potential protective effect of inclisiran on diabetes-associated skeletal muscle remodeling and identifying PDK4 as a potential molecular factor associated with these skeletal muscle alterations.
Zhen-Hong He, Han-Yu Li, Lin-Min Ran et al.
· Scientific Reports · 0 citations