Aug 2026
DiConSite: A Unified Topology-Adaptive Architecture for Protein Binding Site Prediction Across Ligand Modalities.
By combining protein language model embeddings with topology-adaptive geometric reasoning, DiConSite offers a reusable framework for residue-level protein interaction analysis and achieves consistently strong and often best-performing results, while improving robustness to structural uncertainty and cross-modal variati...
Shou-Zhi Chen, Zhen-Chao Tang, Lin-Lin You et al.
· IEEE Transactions on Pattern... · 1 citation