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Author

Lin-Lin Yan

2 papers indexed here

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Open access Oct 2026

Targeting MMGT1 enhances immunotherapy efficacy in triple-negative breast cancer.

The role of senescent tumor cells in modulating the immune microenvironment and influencing immunotherapy efficacy remains poorly understood. In this study, we investigate the function of the senescence-associated gene membrane magnesium transporter 1 (MMGT1) in triple-negative breast cancer (TNBC) immunotherapy. MMGT1...

Shao-Qing Liu, Hong-Bing Liu, Meng-Ying Zhang et al. · 0 citations
Open access Aug 2026

Reprogramming pulmonary B cells by ANXA1 silencing halts lung metastatic niche formation in breast cancer

Lung metastasis remains a determinant of poor prognosis and survival in breast cancer and is understood to depend on a permissive pulmonary immune niche rather than tumor cell traits alone. Here, we developed a host-directed RNA interference strategy to modulate this niche by reprogramming pulmonary B cells for breast...

Xiao-Bo Gao, Meng Zhang, Xiao-Han Yao et al. · 0 citations

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