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Lin-Le Xu

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Open access Oct 2026

SARS-CoV-2 spike protein enhances HBV replication via autophagy and aggravates inflammation in CHB patients with liver dysfunction

ABSTRACT This study investigated the effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S protein) on hepatitis B virus (HBV) replication and immune function in patients with chronic hepatitis B (CHB), aiming to elucidate the underlying mechanisms of S protein–HBV interaction. Th...

Liang-Juan Chen, Yu-Fen Jiang, Xing-Zhong Miao et al. · 0 citations

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